Treatment with Cosequin ® of Bilateral Coxofemoral Osteoarthritis in a Great Dane

common cause of degenerative joint disease (DJD) in dogs, is a chronic, progressive, noninfectious joint disorder that leads to degeneration of articular cartilage and proliferative changes. Damage to articular cartilage may result from abnormal stresses that disrupt the normal articular surface, in turn leading to joint instability. Consequently, the normal wear pattern as well as the turnover of articular matrix are accelerated. This process is also accelerated by cytokines and prostaglandins released by synovial cells into the joint. As a result, the joint capsule thickens and periarticular osteophytes form in an effort to improve joint stability.